Jan 12, 2010
A baby anaconda, captured at the end of Anaconda 3: Offspring, is being used for experiments by a scientist. He creates a hybrid of the blood orchids from Borneo that enabled the anaconda to grow so large and live so long, and creates a serum for cell regeneration. When he disappears and the snake escapes, Murdoch sends a team to find him. Dr. Amanda Hayes also goes in search of him, determined to destroy the serum and kill the snake.
The two groups encounter more people who get dragged into the search for the snake, which has been split in two by someone attempting to kill it. Due to the serum, the anacondas can no longer die without significant damage to their internal organs. In the process, most of the people are eaten by the snake. Suddenly Murdoch appears and discovers that the serum works, but is killed by the anaconda.
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The anaconda is in pursuit on the survivors who are in a car with one of Murdoch’s hunters, Eugene. Amanda kicks him out of the car with two grenades in hand. While the snake devours him the snake is blown to bits. As they leave another anaconda appears and slithers into the forest
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